Isotopically Labeled Compounds
Sigma Aldrich Fine Chemicals Biosciences Methanol-d4 99.8 atom D c10G
Methanol-d4 is a deuterated NMR solvent containing 0.03 % (v/v) TMS (trimethylsilane). It is useful in NMR-based research and analyses.
Medchemexpress LLC Febuxostat-d7 | 1285539-74-3 | 99.1% | C16H9D7N2O3S | 1 MG
Febuxostat-d7 is a deuterium labeled form of Febuxostat, a selective xanthine oxidase inhibitor with a Ki of 0.6 nM. It serves as a tracer and an internal standard for quantitative analysis. Deuterated compounds are used as tracers for quantitation during drug development and can affect pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium labeled Febuxostat
- Selective xanthine oxidase inhibitor with a Ki of 0.6 nM
- For research use only
Medchemexpress LLC Deruxtecan-d5 | 1599440-13-7 | 98.4% | 1039.08 | 1 MG
Deruxtecan-d5 is a deuterium-labeled version of Deruxtecan. It is an ADC (Antibody-Drug Conjugate) drug-linker conjugate composed of a DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Tamoxifen-d3 hydrochloride | 54965-24-1 | 99.0% | 410.99 | 1 MG
Tamoxifen-d3 hydrochloride is a deuterated labeled Tamoxifen that functions as an orally active, selective estrogen receptor modulator (SERM). It blocks estrogen action in breast cells and activates estrogen activity in other cells, such as bone, liver, and uterine cells. This compound is also a potent Hsp90 activator, enhancing its molecular chaperone ATPase activity. It potently inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 values of 0.1 μM and 1.8 μM, respectively. It activates autophagy and induces apoptosis, and can induce gene knockout of CreER(T2) transgenic mouse.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories Dimethyl Sulfoxide-D6 | 2206-27-1 | MFCD00002090 | 5 mL
Dimethyl Sulfoxide-D6 | 99.5% | 84.17 | 2206-27-1 | MFCD00002090 | 5 mL
Medchemexpress LLC Diclofenac-d4 | 153466-65-0 | C14H7D4Cl2NO2 | 5 MG
Diclofenac-d4 is a deuterium labeled form of Diclofenac, a potent and nonselective anti-inflammatory agent that acts as a COX inhibitor. It has been shown to induce apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade. Incorporating stable heavy isotopes like deuterium allows for its use as a tracer for quantitative analysis during drug development, potentially influencing pharmacokinetic and metabolic profiles.
- Deuterium labeled compound
- Potent and nonselective anti-inflammatory agent
- Acts as a COX inhibitor
- Induces apoptosis of neural stem cells
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Pyrene-d10 | 1718-52-1 | C16D10 | 50 MG
Pyrene-d10 is a deuterium labeled form of Pyrene, designed for research use only.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- For research applications only
Medchemexpress LLC Rac-ruxolitinib-d9 | 2469553-67-9 | 99.4% | 315.42 | C17H9D9N6 | 1 MG
(Rac)-Ruxolitinib-d9 is the deuterium-labeled racemic form of ruxolitinib (INCB18424), a JAK1/2 inhibitor supplied for research use as an analytical standard or tracer in biochemical and pharmacokinetic studies.
- Deuterium-labeled tracer for isotope labeling and mass spectrometry applications.
- High purity suitable for analytical work (99.4%).
- Provided as a solid, white to yellow, for ease of handling and storage.
- Available in small research sizes suitable for standards (1 mg and 5 mg).
- Documented identifiers: CAS number 2469553-67-9; molecular formula C17H9D9N6; molecular weight 315.42.
- Storage guidance: long-term at -20°C under nitrogen; in solvent: -80°C for 6 months, -20°C for 1 month (stored under nitrogen).
Medchemexpress LLC Quinolinic acid-d3 | 138946-42-6 | MFCD13189065 | 99.9% | 170.14 g/mol | C7H2D3NO4 | 1 MG
Quinolinic acid-d3 is the deuterium-labeled isotopologue of quinolinic acid intended for analytical and research use as a tracer and internal standard. It acts as an NMDA receptor agonist analog and is formulated for accurate quantitative analysis in spectroscopy and mass spectrometry workflows.
- High isotopic labeling suitable for tracer and internal standard applications.
- High purity (99.9%) for reliable quantitative results.
- Molecular weight ~170.14 g/mol supporting precise mass calibration.
- Soluble in DMSO and water with ultrasonic assistance for flexible sample prep.
- Compatible with NMR, GC-MS, and LC-MS quantitative workflows.
Medchemexpress LLC Treprostinil-d9 | 2747918-14-3 | MFCD23144256 | 99.8% | 399.57 g/mol | C23H25D9O5 | 5 MG
Treprostinil-d9 is a deuterium-labeled analogue of treprostinil used as a stable-isotope internal standard for analytical and pharmacokinetic studies. It is intended for use in mass spectrometry, method development, and quantitative bioanalysis where accurate normalization and peak identification are required.
- Deuterium-labeled internal standard for accurate quantitation in MS assays.
- High purity (99.79%) for reliable analytical performance.
- Molecular weight approximately 399.57 g/mol for precise mass calibration.
- Available in small, research-friendly pack sizes (mg scale).
- Suitable for pharmacokinetic and bioanalytical method development.
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Revvity Health Sciences Inc dCTP, [α-32P]- 3000Ci/mmol 10mCi/ml EasyTide, 250 µCi
dCTP, [α-32P]- 3000Ci/mmol 10mCi/ml EasyTide, 250 µCi
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Revvity Health Sciences Inc Hemicholinium-3 Diacetate Salt, [Methyl-3H]-, 250µCi (9.25MBq)
Hemicholinium-3 Diacetate Salt, [Methyl-3H]-, 250µCi (9.25MBq)
Sigma Aldrich Fine Chemicals Biosciences D-Glucose-13C6 >=99 atom % 13C, >=99% (CP) | 110187-42-3 | MFCD00037544 | 3G
D-Glucose-13C6 >=99 atom % 13C, >=99% (CP) | Purity: >=99% (CP) | Mol Wt: 186.11 | 110187-42-3 | MFCD00037544 | 3G
CAMBRIDGE ISOTOPE LABORATORIES METABOLOMICS QRESS UNLABEL KIT
NC1934388 METABOLOMICS QRESS UNLABEL KIT